Simemory

Pharmaceutical Form

Presentation: 10 blister packs, each containing 10 tablets, packed in a cardboard box with a patient information leaflet.

Composition

Each tablet contains:

• Korean Ginseng Powder: 150 mg
• Ginkgo Biloba Leaf Powder: 50 mg
• Ginkgo Biloba Leaf Extract: 30 mg
• Standardization: Each tablet is standardized to 19.2 mg of total flavonol glycosides.

Indications

• Improves cerebral and peripheral blood circulation (brain, arms, and legs).
• Enhances memory and cognitive function.
• Boosts focus and aids in retaining mental information.
• Prevents mental fatigue and reduces forgetfulness.

Dosage and Administration

• Recommended Dose: 1-2 tablets daily after meals (preferably 1 tablet after breakfast and 1 tablet after lunch).
• For optimal results, the product should be used for one month.

Pharmacological Effects and Mechanism of Action

Korean Ginseng

• The root is rich in bioactive compounds and is utilized for improving resistance to environmental stress, enhancing physical endurance, preventing muscular damage, and supporting memory and concentration.
• Beneficial in conditions like Alzheimer’s disease and is used as a general tonic.

Ginkgo Biloba

• The leaves are used for memory loss and dementia, particularly in age-related cerebral vascular insufficiency.
• Improves blood circulation, especially to capillaries in the central nervous system, eyes, and ears.
• Enhances cognitive function, mood, and auditory health by increasing microvascular blood flow.

Adverse Effects

• Ginseng: Generally well-tolerated at therapeutic doses but may cause insomnia in some individuals.
• Ginkgo Biloba:
  • May cause mild gastrointestinal discomfort, headache, dizziness, palpitations, constipation, or allergic skin reactions.
  • Rarely associated with spontaneous bleeding.

Drug Interactions

• Ginkgo Biloba:
  • May reduce the effectiveness of alprazolam.
  • Inhibits platelet aggregation, enhancing the effects of antiplatelet medications.
  • May increase serotonin reuptake; concurrent use with serotonergic antidepressants could theoretically decrease their efficacy.
  • Combined use with buspirone or fluoxetine may induce mild mania in depressive patients.
  • Co-administration with trazodone may result in coma.

Use During Pregnancy and Lactation

Not recommended during pregnancy and lactation.

Contraindications and Precautions

• Not suitable for individuals under 18 years of age.
• Contraindicated in:
  • Women with a history of breast, uterine, or ovarian cancer, endometriosis, or uterine fibroids.
  • Patients with a history of organ transplantation due to potential interactions with immunosuppressive drugs.
  • Conditions involving bleeding disorders or thrombosis.
• Discontinue at least two weeks prior to surgery to prevent bleeding risks.
• Ginkgo Biloba extract may alter insulin secretion and metabolism, potentially affecting blood glucose levels in type 2 diabetes patients. Use with caution in diabetics.

Storage Conditions

• Store below 30°C, away from light and moisture.
• Keep out of reach of children.