Herpesim

Product Name: Herpesim Cream (Simorgh Darou)
Formulation: Topical Cream
Packaging: 1 tube of 10 grams, with an instruction leaflet inside a cardboard box

Composition (Active Ingredients)

Each 1 gram of Herpesim Cream contains:

• Propolis Extract: 30 mg

Other Ingredients:

• Vaseline
• Stearic Acid
• Beeswax
• Methyl Paraben
• Propyl Paraben
• Lanolin
• Alcohol
• Triethanolamine
• Glycerin Monostearate
• Paraffin
• Glycerin
• Purified Water

Standardized Based on 0.4 mg Flavonoids per 1 gram of Cream

Indications

Herpesim Cream is indicated for:

Rapid relief of cold sore symptoms (herpes simplex)

Dosage and Administration

Recommended Dosage: Apply a sufficient amount of the product to the cold sore lesion up to 5 times a day for 5 to 7 days, or as directed by your healthcare provider.

Precautions and Contraindications

• Drug, Supplement, and Herbal Interactions:
  Consult your doctor or pharmacist before using this product if you are taking any medications, supplements, or herbal products, or if you have any chronic medical conditions.
• Allergy Warning:
  Discontinue use if you are allergic to any of the ingredients in this product.
  • Do not use if you experience any irritation or sensitivity around the lips.
  • People with an allergy to honeycomb products (e.g., propolis) may experience allergic reactions.
• Pregnancy and Lactation:
  Due to a lack of sufficient data, it is recommended to avoid using this product during pregnancy and breastfeeding.
• Eye Contact:
  Avoid contact with the eyes.
• Use in Children:
  Use in individuals under 12 years of age should be done only under the supervision of a healthcare provider.

Side Effects

When used as directed, Herpesim Cream is safe and effective. However, as with all treatments, some individuals may experience unwanted side effects. The most common side effects may include:

• Skin rash or irritation around the lips
• Contact allergic reactions

If any adverse reactions occur, consult your doctor or pharmacist.

Drug Interactions

No significant drug interactions have been reported with the use of this product.

Use in Pregnancy and Lactation

Due to insufficient data, it is advised to avoid using this product during pregnancy and lactation.

Pharmacological Effects and Mechanism of Action

Propolis is a resinous substance created by bees, consisting of a mixture of bee saliva, beeswax, and plant resins. Bees use propolis to seal cracks in the hive and protect it from intruders.

• Antimicrobial Properties: Propolis may protect bees from pathogens, and it has been shown to possess antimicrobial, anti-inflammatory, and wound-healing properties.
• Flavonoids: Propolis contains flavonoids such as pinocembrin, galangin, pinobanksin, and pinobanksin-3-acetate, which contribute to its antibacterial and anti-inflammatory effects.
• Herpes Treatment: Research has indicated that propolis may be effective in treating minor wounds, oral hygiene, inflammation, and cold sores caused by herpes simplex virus types HSV-1 and HSV-2.