Simosed Syrup

Active Ingredients in Simosed Syrup (per 5 mL)

Passionflower extract (Passiflora incarnata): 48 mg

Lemon balm extract (Melissa officinalis): 45 mg

Chamomile extract (Matricaria chamomila): 7 mg

Other Ingredients: Sucralose, Potassium sorbate, Xanthan gum, Essence, Purified water

Standardized based on 0.29% Hesperidin.

Indications for Simosed Syrup

Relief from insomnia (with or without restlessness).

Reduces the time it takes to fall asleep.

Relieves symptoms of depression, irritability, and aggression in both children and adults.

Dosage Instructions

Shake the bottle well before use. Take 30-60 minutes before bedtime.

6 months to 12 months: 5 mL

1 to 2 years: 10 mL

2 to 3 years: 15 mL

3 to 6 years: 20 mL

Adults: 30 mL or as directed by a physician.

For optimal results, use for at least 3 weeks. The product may settle or separate, but this does not affect its quality.

Pharmacological Effects and Mechanism of Action

Passionflower: Has sedative and calming effects, used for insomnia, anxiety, neural pain, muscle tension, and certain respiratory issues like bronchospasm.

Lemon balm: Helps alleviate anxiety, insomnia, restlessness, hyperactivity, lack of focus, and digestive or heart issues stemming from nervous conditions. Contains terpenes that quickly pass the blood-brain barrier and activate GABA receptors, promoting relaxation.

Chamomile: Used for insomnia and as an anxiolytic. Studies show chamomile’s apigenin component binds to GABA receptors, producing effects similar to benzodiazepines.

Side Effects

No side effects observed with therapeutic doses used for up to one month.

Possible side effects in some individuals may include dizziness, confusion, drowsiness, imbalance, and lack of muscle coordination during movement.

Pregnancy and Breastfeeding

Consult a doctor before using during pregnancy or breastfeeding.

Precautions

Consult with a physician if using other medications for hyperactivity or mood disorders in children.

Not recommended for individuals with peptic ulcers due to potential gastrointestinal side effects.

For best results, use regularly as prescribed. Recommended treatment duration is 3 to 4 weeks, with the possibility of repeating the treatment if necessary.

Drug Interactions

Not recommended for use with midazolam or MAOI drugs.

May interact with CNS depressants. Consult a doctor or pharmacist if using these medications.

Storage

Keep the bottle tightly closed after each use.

Store in a cool place (below 30°C), preferably in the refrigerator, away from light and moisture.

Keep out of reach of children.

Once opened, store in the refrigerator and use within one month.