Simfemalib

Pharmaceutical Form: Simfemalib Tablets – Simorgh Darou

Indications: Enhancing Female Libido

Packaging

Three blister packs, each containing 10 tablets, along with an instruction leaflet, in a cardboard box. Standardized to contain 1.776 mg of Glycyrrhizin per tablet.

Ingredients (per tablet)

• Cocoa Theobromine: 50 mg
• Indole-3-Carbinol: 35 mg
• Ginkgo Biloba: 25 mg
• Damiana Leaf Powder (Turnera diffusa): 25 mg
• Black Cohosh Root Powder (Actaea racemosa): 25 mg
• Red Raspberry Leaf Powder (Rubus Idaeus): 25 mg
• Licorice Root Powder (Glycyrrhiza glabra): 25 mg
• Ginger Root Powder (Zingiber officinale): 25 mg
• Valerian Root Powder (Valeriana officinalis): 25 mg
• Kudzu Root Powder (Pueraria montana): 25 mg
• Korean Ginseng Root Powder (Panax ginseng): 16 mg
• Iron (as Iron Gluconate): 96.29 mg
• Vitamin C (Ascorbic Acid): 10 mg
• Calcium (as Calcium Carbonate): 100 mg
• Zinc (as Zinc Gluconate): 9 mg
• Vitamin E (Alpha-Tocopherol Acetate): 5.48 mg
• Niacin (Niacinamide): 3 mg
• Vitamin A (Palmitate): 3.664 mg
• Pantothenic Acid (as Calcium Pantothenate): 2.1735 mg
• Folate (Folic Acid): 0.8 mg
• Biotin: 0.5 mg
• Vitamin B6 (Pyridoxine Hydrochloride): 0.528 mg
• Vitamin B1 (Thiamine Hydrochloride): 0.224 mg
• Vitamin B2 (Riboflavin): 0.2 mg
• Vitamin B12: 0.012 mg
• L-Arginine (as L-Arginine Hydrochloride): 362.789 mg

Other Excipients: Magnesium Stearate, Dicalcium Phosphate, Microcrystalline Cellulose, Sodium Croscarmellose, Hypromellose

Indications for Use

Assists in enhancing female sexual libido.

Dosage and Administration

One tablet daily after a meal, or as directed by a physician.

Pharmacological Actions and Mechanism of Action

• L-Arginine: An essential amino acid required for protein synthesis, converted in the body to nitric oxide, which causes vasodilation and improves blood flow.
• Damiana: The aerial parts of the plant (stem and leaves) contain 35 compounds, including flavonoids, triterpenoids, saccharides, and glycosides, traditionally used as an aphrodisiac.
• Black Cohosh Root: Traditionally used to alleviate menopausal symptoms and as a nervine, promoting relaxation and reducing stress.
• Ginseng and Damiana, Red Raspberry, Kudzu: These have historically been used in traditional medicine to enhance sexual desire.
• Vitamin C: A water-soluble vitamin with anti-inflammatory and antioxidant properties, supporting immune function.
• Vitamin A: A fat-soluble vitamin essential for growth, vision, immune function, and cellular differentiation.
• Vitamin D: A fat-soluble vitamin crucial for calcium absorption and bone health.
• Vitamin E: An antioxidant that helps prevent free radical damage.
• B-Vitamins: Essential for various metabolic processes, including cell differentiation, amino acid synthesis, and lipid metabolism. Specific functions include:
  • B1 (Thiamine): Stimulates growth, heart muscle strengthening, and brain function.
  • B2 (Riboflavin): Supports general growth, digestion, and nerve function, also plays a role in eye health.
  • B3 (Niacin): Important for blood flow, nerve function, and digestion.
  • B5 (Pantothenic Acid): Vital for the metabolism of carbohydrates, fats, proteins, and amino acids.
  • B6 (Pyridoxine): Important for fatty acid metabolism and nervous system function.
  • B12: Crucial for red blood cell production, central nervous system function, memory, and concentration.

Side Effects

As with any therapeutic product, side effects may occur. Common side effects include headache, dizziness, nausea, diarrhea, gastrointestinal disturbances, blood pressure irregularities, and allergic reactions. Rare and high-dose side effects may include vaginal bleeding, breast pain, and insomnia.

Drug Interactions

Potential interactions with benzodiazepines (e.g., Alprazolam), antiplatelet drugs (e.g., Warfarin), anticonvulsants, antidepressants (e.g., Trazodone, Fluvoxamine), antidiabetic medications, statins (e.g., Atorvastatin), theophylline, verapamil, ibuprofen, and efavirenz.

Contraindications and Precautions

• Consult a physician or pharmacist before use if taking other medications, supplements, or herbs, or if suffering from chronic diseases.
• Discontinue use if allergic to any component.
• Caution is advised for patients with hormonal conditions such as breast or uterine cancer.
• Discontinue use at least two weeks before surgery.
• High doses may cause insomnia.
• Avoid use in immunosuppressive therapy.
• Consult a physician before combining with other products containing iron, zinc, calcium, vitamins A, C, or D.
• Use during pregnancy and breastfeeding should be under medical supervision.

Storage

Store in a dry, cool place, away from light, at temperatures below 30°C. Keep out of reach of children. Close the bottle tightly after use. Protect from freezing.