Simovit Omega3

Form: Oral solution
Packaging: 200 mL bottle with an informational leaflet

Active Ingredients (per 5 mL)

Fish Oil: 4600 mg

Vitamin D3: 800 IU

Vitamin E: 18 IU

Other Ingredients: Sunflower oil, orange essence

Indications for Simovit Omega-3 Syrup

Helps reduce cholesterol

Supports cardiovascular health

Assists in reducing inflammation

Dosage Instructions

Children (5-12 years): 2.5 mL after meals, once daily

Adults: 5 mL after meals, once daily

Shake well before use. Use as directed by a physician.

Precautions

Consult a physician before use if you have any illness, are taking any other medications or supplements, or have allergies to any ingredients.

Pregnant or breastfeeding women should consult a doctor.

Discontinue use two weeks before surgery.

Individuals with conditions like high blood pressure, kidney failure, hemophilia, bipolar disorder, cirrhosis, depression, immune deficiencies, or seafood allergies should consult a doctor before use.

Side Effects

May cause mild gastrointestinal issues such as nausea, diarrhea, fishy taste, bad breath, and burping. These effects can be minimized by taking the syrup with food.

Interactions

Blood pressure medications, contraceptives, anticoagulants, and antiplatelet drugs may have enhanced effects when taken with fish oil.

Orlistat may reduce the absorption of fish oil fatty acids and vitamin E; take this supplement at least 3 hours apart.

Vitamin E may reduce the effectiveness of chemotherapy drugs and increase the absorption of cyclosporine, possibly leading to toxicity.

Vitamin D may interact with aluminum-containing medications, some calcium channel blockers (e.g., diltiazem, verapamil), calcium supplements, and thiazide diuretics, among others.

Anticonvulsants and certain drugs (e.g., amiodarone, cholestyramine) may reduce plasma levels of vitamin D.

Pharmacology and Mechanism of Action

Omega-3: Composed of DHA and EPA, key components for the central nervous system and retina, and promote blood circulation. Fish oil’s anti-inflammatory and antithrombotic effects make it beneficial for cardiovascular diseases. Omega-3 also has blood-thinning properties that may prevent high blood pressure and improve kidney function.

Vitamin E: An essential antioxidant that protects cell membranes and red blood cells from oxidative damage. Its vascular protective effects likely come from preventing LDL oxidation.

Vitamin D: Enhances calcium absorption, which is crucial for bone health and may prevent osteoporosis. Vitamin D also strengthens the immune system and influences inflammatory mediators, benefiting cardiovascular health.

Storage

Keep out of reach of children.

Store in its box, away from light and moisture, at temperatures below 25°C.

After opening, refrigerate and use within 3 months; do not freeze.