Diurclean

Pharmaceutical Form: Diurclean Capsule
Manufacturer: Simorgh Daru
Indication: For bladder and urinary tract health

Standardized to contain a minimum of 0.249 mg total anthocyanins per capsule.

Ingredients per Diurclean Capsule

• Vaccinium macrocarpon (Cranberry) Fruit Powder: 125 mg
• Aloe vera Leaf Powder: 100 mg
• Taraxacum officinale (Dandelion) Leaf Powder: 100 mg
• Juniperus communis (Juniper) Fruit Powder: 75 mg
• Althaea officinalis (Marshmallow) Root Powder: 75 mg
• Zea mays (Corn Silk) Powder: 50 mg
• Equisetum arvense (Horsetail) Aerial Parts Powder: 50 mg
• Rosa canina (Rosehip) Fruit Powder: 50 mg

Indications for Diurclean Capsules

• Support for bladder and urinary tract health
• Diuretic action
• Aid in alleviating urinary tract infections (UTIs)
• Assist in kidney stone expulsion

Dosage Instructions

Adults should take two capsules twice a day, or as directed by a healthcare professional.

Pharmacological Effects and Mechanism of Action

• Cranberry: Exhibits antibacterial activity against urinary tract epithelial cells and may act against other infection-causing bacteria.
• Marshmallow Root: Contains mucilage polysaccharides that exert diuretic, antimicrobial, antispasmodic, and wound-healing effects.
• Corn Silk: Promotes diuresis by increasing sodium and potassium excretion.
• Dandelion: Known for its diuretic effects, it aids in fluid elimination.
• Aloe Vera: Offers anti-inflammatory benefits and supports tissue repair.
• Juniper: Acts as a mild diuretic, aiding in the expulsion of fluids.
• Rosehip: Provides anti-inflammatory effects and supports overall urinary tract health.

Side Effects

• Marshmallow: Oral use may cause hypoglycemia.
• Corn Silk: Prolonged use may lead to reduced potassium levels.
• Aloe Vera: May cause acute hepatitis in some cases due to increased sensitivity.
• Juniper: May cause hypotension or inflammation, and may affect blood glucose levels in diabetic patients.
• Rosehip: Potential side effects include headaches, insomnia, drowsiness, anaphylaxis, asthma, and rhinitis.

Drug Interactions

• Diabetic medications: This product may interact due to the presence of Juniper, Corn Silk, Marshmallow, Horsetail, and Aloe Vera.
• Warfarin: The presence of Corn Silk, Cranberry, Aloe Vera, and Rosehip may interfere with warfarin efficacy due to vitamin K content in Corn Silk and enhanced sensitivity of clotting factors to warfarin.
• Nifedipine: Cranberry may reduce the metabolism of nifedipine, increasing the risk of side effects.
• Diuretics: Potassium-sparing diuretics may interact with Dandelion due to its potassium content, potentially leading to hyperkalemia.
• Fluoroquinolone antibiotics: Dandelion may lower fluoroquinolone levels, reducing their effectiveness.
• Digoxin: Excessive Aloe Vera may reduce potassium, increasing the risk of digoxin toxicity.
• Thiazide diuretics: Horsetail may enhance the risk of hypokalemia when used with diuretics like chlorthalidone, furosemide, and hydrochlorothiazide.

Contraindications and Recommendations

• Blood sugar control: Marshmallow may interfere with blood glucose regulation.
• Kidney stones: Individuals with kidney stones should avoid this product due to the presence of Cranberry.
• Bleeding disorders: Use caution with Dandelion and Rosehip in patients with bleeding disorders.
• Aloe Vera: Contraindicated in cases of intestinal obstruction, acute gastrointestinal inflammation, appendicitis, or unexplained abdominal pain.
• Diabetes: Use with caution in diabetic patients due to the presence of Horsetail, Juniper, Rosehip, and Cranberry.
• Pregnancy and breastfeeding: Avoid use during pregnancy and breastfeeding.
• Vitamin C: Rosehip may increase the risk of oxalate stone formation due to its vitamin C content.
• Hypokalemia: Caution in patients with low potassium levels due to Horsetail’s effects on potassium.
• Thiamine deficiency: Horsetail may increase the risk of thiamine deficiency.
• Hemorrhoids and kidney disorders: Aloe Vera should be avoided in individuals with hemorrhoids or kidney conditions.

Precautions

• Discontinue the product at least two weeks before surgery.
• Keep out of reach of children.
• Do not exceed the recommended dosage.
• Store in a cool, dry place at temperatures below 25°C.