Calendula 15

Packaging

30 g tube of cream with a leaflet inside a cardboard box.

Active Ingredients

Calendula flower extract (5:1) (Calendula officinalis): 5 mg

Calendula flower oil extract (Calendula officinalis): 10.2 mg

Lavender oil: 1 mg

Other Ingredients: Propylparaben, Methylparaben, Cetyl Alcohol, Paraffin, Stearic Acid, Glycerin, Beeswax, Lanolin, Purified Water

Standardization

Each gram contains a minimum of 0.208 mg of flavonoids.

Indications

Wound healing and reduction of skin inflammation.

Dosage and Administration

Clean the affected area with water, then apply a sufficient amount of cream to the desired area 2-3 times daily or as directed by a physician.

Precautions and Contraindications

Consult a healthcare provider before use if you are taking any medications, supplements, or herbs, or have any chronic health conditions.

Discontinue use if hypersensitivity to any ingredient occurs.

Use with caution during pregnancy; avoid use during breastfeeding due to limited safety data.

For external use only; avoid application around the eyes.

Avoid use around wound edges if inflammation occurs.

Use with caution in pubescent boys, as rare cases of gynecomastia have been reported with lavender oil.

Side Effects

While generally well-tolerated, possible side effects may include contact dermatitis and local skin reactions. Calendula may cause rare inflammatory responses around wounds. Lavender oil can cause contact dermatitis and, rarely, gynecomastia in young males. Consult a healthcare provider if any adverse reactions occur.

Drug Interactions

No significant interactions have been reported for this topical product.

Use During Pregnancy and Lactation

Use with caution during pregnancy; avoid during lactation due to limited safety data.

Pharmacology and Mechanism of Action

Calendula: The active part is the flower, which contains active compounds like squalene, calenduloside B, minerals, carbohydrates, lipids, phenolic acids, flavonoids, coumarins, sterols, steroids, amino acids, and resins. Calendula is used for wound healing due to its anti-inflammatory effects, largely attributed to faradiol monoester. Water-soluble flavonoids are believed to enhance wound healing. Some animal studies suggest that allantoin in calendula may promote cell proliferation in damaged skin tissues.

Lavender: The active parts include flowers, leaves, and oil, with active compounds like cineole (from essential oil) and camphor (from leaves). Animal studies indicate that topical lavender oil promotes wound healing and accelerates skin repair through its anti-inflammatory and antibacterial effects.

Storage Conditions

Store in the original box, away from light, moisture, and at a temperature below 30°C. Keep out of reach of children.