Sim Pregna

  • Relieves cough
  • Soothes throat irritation
  • Eases dry cough
  • Improves hoarseness
  • Alleviates cold symptoms during pregnancy and lactation
  • Enhances immune system function

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Indication

Relief of cold symptoms (suitable for use during pregnancy and lactation).

Dosage Form

120 mL syrup in a cardboard box with a patient information leaflet.

Ingredients (Per 5 mL)

  • Vitamin C: 34 mg
  • Zinc (as Zinc Gluconate): 1.65 mg
  • Honey: 1250 mg

Uses:

  • Relieves cough
  • Soothes throat irritation
  • Eases dry cough
  • Improves hoarseness
  • Alleviates cold symptoms during pregnancy and lactation
  • Enhances immune system function

Dosage and Administration

  • Adults, children over 12 years, and pregnant women: Take two teaspoons (10 mL) every 8 hours.
  • Safe for use during pregnancy and lactation.
  • Not suitable for children under one year due to honey content.

Pharmacological Effects and Mechanism of Action

  • Vitamin C: Plays a crucial role in various physiological functions, including oxidation-reduction reactions and cellular respiration. It is a well-known antioxidant and enhances immune system performance.
  • Zinc: Essential for immune function, with clinical studies demonstrating a significant reduction in the duration of colds with zinc supplementation.
  • Honey: Shown in clinical studies to significantly improve cough associated with colds and allergies, often outperforming diphenhydramine and dextromethorphan in relieving cough.

Adverse Effects

No specific adverse effects have been observed with the recommended dosage.

Drug Interactions

  • Zinc absorption may be reduced by iron supplements, tetracyclines, and phytate-containing foods. Zinc can, in turn, decrease the absorption of copper, fluoroquinolones (e.g., ciprofloxacin), iron, and tetracyclines. A minimum interval of two hours between zinc supplements and tetracyclines is recommended.
  • High doses of vitamin C can interact with warfarin.

Use During Pregnancy and Lactation

Safe for use during pregnancy and lactation.

Contraindications and Precautions

  • Use cautiously in diabetic patients due to the presence of vitamin C and zinc.
  • In patients with kidney stones or cancer, use vitamin C-containing products with caution and under medical supervision.

Storage Conditions

Store below 30°C, away from light, moisture, and out of reach of children.

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